The best emails I get start with "I disagree." The next-best start with "we should build something." Either is welcome — and both will be read by me.
I read every message. I reply to most. The fastest way to get a thoughtful reply is to be specific about what you'd like to talk about — vague intros wait the longest.
For press: write "press" in the subject. For speaking: include date, audience size, and the question you want me to wrestle with.